Entrez

Information about Entrez

The Entrez Global Query Cross-Database Search System is a powerful federated search engine, or web portal that allows users to search many discrete health sciences databases at the National Center for Biotechnology Information (NCBI) website. NCBI is part of the National Library of Medicine (NLM), itself a department of the National Institutes of Health (NIH) of the United States government. Entrez also happens to be the French word for the second person plural form of the verb "to enter", meaning literally "come in".

Entrez Global Query is an integrated search and retrieval system that provides access to all databases simultaneously with a single query string and user interface. Entrez can efficiently retrieve related sequences, structures, and references. The Entrez system can provide views of gene and protein sequences and chromosome maps. Some textbooks are also available online through the Entrez system.

Features

The Entrez front page provides, by default, access to the global query. All databases indexed by Entrez can be searched via a single query string, supporting boolean operators and search term tags to limit parts of the search statement to particular fields. This returns a unified results page, that shows the number of hits for the search in each of the databases, which are also links to actual search results for that particular database.

Entrez also provides a similar interface for searching each particular database and for refining search results. The Limits feature allows the user to narrow a search a web forms interface. The History feature gives a numbered list of recently performed queries. Results of previous queries can be referred to by number and combined via boolean operators. Search results can be saved temporarily in a Clipboard. Users with a MyNCBI account can save queries indefinitely and also choose to have updates with new search results e-mailed for saved queries of most databases. It is widely used in the field of biotechnology to enhance the knowledge of students worldwide.

Databases

Entrez searches the following databases:
  • PubMed: biomedical literature citations and abstracts, including Medline - articles from (mainly medical) journals, often including abstracts. Links to PubMed Central and other full-text resources are provided to articles from the 1990s.
  • PubMed Central: free, full text journal articles
  • Site Search: NCBI web and FTP web sites
  • Books: online books
  • OMIM: online Mendelian Inheritance in Man
  • OMIA: online Mendelian Inheritance in Animals
  • Nucleotide: sequence database (GenBank)
  • Protein: sequence database
  • Genome: whole genome sequences and Mapping
  • Structure: three-dimensional macromolecular structures
  • Taxonomy: organisms in GenBank Taxonomy
  • SNP: single nucleotide polymorphism
  • Gene: gene-centered information
  • HomoloGene: eukaryotic homology groups
  • PubChem Compound: unique small molecule chemical structures
  • PubChem Substance: deposited chemical substance records
  • Genome Project: genome project information
  • UniGene: gene-oriented clusters of transcript sequences
  • CDD: conserved protein domain database
  • 3D Domains: domains from Entrez Structure
  • UniSTS: markers and mapping data
  • PopSet: population study data sets (epidemiology)
  • GEO Profiles: expression and molecular abundance profiles
  • GEO DataSets: experimental sets of GEO data
  • Cancer Chromosomes: cytogenetic databases
  • PubChem BioAssay: bioactivity screens of chemical substances
  • GENSAT: gene expression atlas of mouse central nervous system
  • Probe: sequence-specific reagents
  • NLM Catalog: NLM bibliographic data for over 1.2 million journals, books, audiovisuals, computer software, electronic resources, and other materials resident in LocatorPlus (updated every weekday).

Accessing Entrez

In addition to using the search engine forms to query the data in Entrez, NCBI provides the Entrez Programming Utilities (eUtils) for more direct access to query results. The eUtils are accessed by posting specially formed URLs to the NCBI server, and parsing the XML response. There is also an eUtils SOAP interface.

See also

  • Chemistry resources

External link

Databases supported by Bioinformatic Harvester
NCBI-BLAST | CDD | Ensembl | Entrez | GFP-cDNA | Genome_browser | GeneCards | Google_Scholar | GoPubMed | HomoloGene | iHOP | IPI | OMIM | Mitocheck | PSORT | PolyMeta | UniProt | SOURCE | SOSUI | RZPD | STRING | SMART | ZFIN |
Federated search is the simultaneous search of multiple online databases and is an emerging feature of automated, Web-based library and information retrieval systems. It is also often referred to as a portal, as opposed to simply a Web-based search engine.
..... Click the link for more information.
web portal is a site that functions as a point of access to information on the World Wide Web. Portals present information from diverse sources in a unified way. Popular portals are MSN, Yahoo, and AOL.
..... Click the link for more information.
Health science is the applied science dealing with health, and it includes many subdisciplines. See also health science academic disciplines.

There are two approaches to health science: the study and research of the human body and health-related issues to understand
..... Click the link for more information.
The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health. The NCBI is located in Bethesda, Maryland and was founded in 1988.
..... Click the link for more information.
The United States National Library of Medicine (NLM), operated by the United States federal government, is the world's largest medical library.[1] The collections of the National Library of Medicine include more than seven million books, journals, technical
..... Click the link for more information.
National Institutes of Health (NIH) is an agency of the United States Department of Health and Human Services and is the primary agency of the United States government responsible for biomedical research.
..... Click the link for more information.
United States of America

This article is part of the series:
Politics and government of
the United States


Federal government
Constitution
Taxation

President Vice President
Cabinet


Congress
Senate
..... Click the link for more information.
primary structure of a biological molecule is the exact specification of its atomic composition and the chemical bonds connecting those atoms (including stereochemistry). For a typical unbranched, un-crosslinked biopolymer (such as a molecule of DNA, RNA or typical intracellular
..... Click the link for more information.
In biochemistry and chemistry, the tertiary structure of a protein or any other macromolecule is its three-dimensional structure, as defined by the atomic coordinates.[1]

Relationship to primary sequence


..... Click the link for more information.
For a non-technical introduction to the topic, see .
A gene is a locatable region of genomic sequence, corresponding to a unit of inheritance, which is associated with regulatory regions, transcribed regions and/or other functional sequence regions.
..... Click the link for more information.
Proteins are large organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds between the carboxyl and amino groups of adjacent amino acid residues.
..... Click the link for more information.
Figure 1: A representation of a condensed eukaryotic chromosome, as seen during cell division.]] A chromosome is a single large macromolecule of DNA, and constitutes a physically organized form of DNA in a cell.
..... Click the link for more information.
PubMed is a free search engine offering access to the MEDLINE database of citations and abstracts of biomedical research articles. The core subject is medicine, and PubMed covers fields related to medicine, such as nursing and other allied health disciplines.
..... Click the link for more information.
MEDLINE (Medical Literature Analysis and Retrieval System Online) is an international literature database of life sciences and biomedical information. It covers the fields of medicine, nursing, pharmacy, dentistry, veterinary medicine, and health care.
..... Click the link for more information.
A medical journal is a scientific journal devoted to the field of medicine. Most medical journals are peer-reviewed. Medical journals commonly arose as the journal of societies, such as the precursors of the British Medical Association, and would originally be collections of
..... Click the link for more information.
scientific journal is a publication intended to further the progress of science, usually by reporting new research. Most journals are highly specialized, although some of the oldest journals such as Nature
..... Click the link for more information.
PubMed Central is a free digital database of full-text scientific literature in biomedical and life sciences. It can be reached at [1] .

It grew from the online Entrez PubMed biomedical literature search system. PubMed Central was developed by the U.S.
..... Click the link for more information.
Centuries: 19th century - 20th century - 21st century

1960s 1970s 1980s - 1990s - 2000s 2010s 2020s
1990 1991 1992 1993 1994
1995 1996 1997 1998 1999

- -
-
For the band, see .

..... Click the link for more information.
PubMed Central is a free digital database of full-text scientific literature in biomedical and life sciences. It can be reached at [1] .

It grew from the online Entrez PubMed biomedical literature search system. PubMed Central was developed by the U.S.
..... Click the link for more information.
Mendelian inheritance (or Mendelian genetics or Mendelism) is a set of primary tenets relating to the transmission of hereditary characteristics from parent organisms to their children; it underlies much of genetics.
..... Click the link for more information.
The term OMIA has several meanings:
  • Geographically, it refers to a Peruvian district
  • In biology, OMIA stands for Online Mendelian Inheritance in Animals, an online database of animal phenotypes.

..... Click the link for more information.
The GenBank sequence database is an open access, annotated collection of all publicly available nucleotide sequences and their protein translations. This database is produced at National Center for Biotechnology Information (NCBI) as part of the International Nucleotide
..... Click the link for more information.
The introduction to this article provides insufficient context for those unfamiliar with the subject matter.
Please help [ improve the introduction] to meet Wikipedia's layout standards.

..... Click the link for more information.
PubChem is a database of chemical molecules. The system is maintained by the National Center for Biotechnology Information (NCBI), a component of the National Library of Medicine, which is part of the United States National Institutes of Health (NIH).
..... Click the link for more information.
PubChem is a database of chemical molecules. The system is maintained by the National Center for Biotechnology Information (NCBI), a component of the National Library of Medicine, which is part of the United States National Institutes of Health (NIH).
..... Click the link for more information.
Genome projects are scientific endeavours that ultimately aim to determine the complete genome sequence of an organism (be it an animal, a plant, a fungus, a bacterium, an archaean, a protist or a virus).
..... Click the link for more information.
UniGene is an NCBI database of the transcriptome and thus, despite the name, not primarily a database for genes. Each entry is a set of transcripts that appear to stem from the same transcription locus (i.e. gene or expressed pseudogene).
..... Click the link for more information.
Epidemiology is the study of factors affecting the health and illness of populations, and serves as the foundation and logic of interventions made in the interest of public health and preventive medicine.
..... Click the link for more information.
NCBI may refer to:
  • National Center for Biotechnology Information, part of the U.S. National Institutes of Health
  • National Coalition Building Institute, a U.S. non-profit training group

..... Click the link for more information.
Simple Object Access Protocol, and lately also Service Oriented Architecture Protocol, but is now simply SOAP. The original acronym was dropped with Version 1.2 of the standard, which became a W3C Recommendation on June 24 2003, as it was considered to be misleading.
..... Click the link for more information.

This article is copied from an article on Wikipedia.org - the free encyclopedia created and edited by online user community. The text was not checked or edited by anyone on our staff. Although the vast majority of the wikipedia encyclopedia articles provide accurate and timely information please do not assume the accuracy of any particular article. This article is distributed under the terms of GNU Free Documentation License.