Gatterman-Koch reaction

The Gattermann-Koch reaction, named for the German chemists Ludwig Gattermann and Julius Arnold Koch,[1] in organic chemistry refers to a Friedel-Crafts acylation reaction in which carbon monoxide and hydrochloric acid are used in-situ with Friedel-Crafts catalyst, namely AlCl3 to produce a benzaldehyde-derivative from a benzene-derivative in one step.[2] Benzaldehyde and many aromatic aldehydes are conveniently synthesized by this reaction. Presence of traces of copper(I) chloride are also needed.

See also

References

1. ^ Gattermann, L.; Koch, J. A. (1897). "Eine Synthese aromatischer Aldehyde". Ber. 30. DOI:10.1002/cber.18970300288.Ber.&rft.date=1897&rft.volume=30&rft.au=Gattermann,%20L.%3B%20Koch,%20J.%20A.&rft_id=info:doi/10.1002%2Fcber.18970300288"> 
2. ^ LI Jie Jack (2003). Name Reactions: A Collection of Detailed Reaction Mechanisms (available on Google Books), 2nd edition, Springer, 157. ISBN 3540402039.Springer&rft.pages=157&rft.isbn=3540402039&rft_id=http%3A%2F%2Fbooks.google.com%2Fbooks%3Fid%3D6mZJ3084ouAC%26pg%3DPA157%26lpg%3DPA157%26dq%3D%2522gattermann%2Bkoch%2522%2Breaction%26source%3Dweb%26ots%3Dku9m3vLfrP%26sig%3DOWVDwJZ1wPRnIDhenbcBL9Dr9KI%23PPA157,M1"> 
Ludwig Gattermann
Born March 20 1860(1860--)
Goslar, Germany
Died May 20 1920 (aged 60)
Freiburg, Germany
Residence Germany
..... Click the link for more information.
Organic chemistry is a specific discipline within chemistry which involves the scientific study of the structure, properties, composition, reactions, and preparation (by synthesis or by other means) of chemical compounds consisting primarily of carbon and hydrogen, which may
..... Click the link for more information.
The Friedel-Crafts reactions are a set of reactions developed by Charles Friedel and James Crafts in 1877.[1] There are two main types of Friedel-Crafts reactions: alkylation reactions and acylation reactions.
..... Click the link for more information.
Carbon monoxide, with the chemical formula CO, is a colorless, odorless, and tasteless gas. It is the product of the incomplete combustion of carbon-containing compounds, notably in internal-combustion engines.
..... Click the link for more information.
In situ is a Latin phrase meaning in the place. It is used in many different contexts.

Aerospace

In the aerospace industry equipment on board aircraft must be tested "in situ" or in place to confirm everything functions properly as a system.
..... Click the link for more information.
Aluminium chloride (AlCl3) is a compound of aluminium and chlorine. The solid has a low melting and boiling point, and is covalently bonded. It sublimes at 178 °C.
..... Click the link for more information.
Benzaldehyde (C6H5CHO) is a chemical compound consisting of a benzene ring with an aldehyde substituent. It is the simplest representative of the aromatic aldehydes and one of the most industrially used members of this family of compounds.
..... Click the link for more information.
aldehyde is an organic compound containing a terminal carbonyl group. This functional group, which consists of a carbon atom which is bonded to a hydrogen atom and double-bonded to an oxygen atom (chemical formula O=CH-), is called the aldehyde group.
..... Click the link for more information.
Copper(I) chloride (quite commonly called cuprous chloride), is the lower chloride of copper, with the formula CuCl. It occurs naturally as the mineral nantokite.
..... Click the link for more information.
The Friedel-Crafts reactions are a set of reactions developed by Charles Friedel and James Crafts in 1877.[1] There are two main types of Friedel-Crafts reactions: alkylation reactions and acylation reactions.
..... Click the link for more information.
The Gattermann rection, named for the German chemist Ludwig Gattermann, in organic chemistry refers to a reaction of hydrocyanic acid with an aromatic compound, in this case benzene, under catalysis with Friedel-Crafts catalyst (aluminium chloride).
..... Click the link for more information.
Chemische Berichte (usually abbreviated as Ber. or Chem. Ber.) is a German-language scientific journal featuring chemistry of all disciplines. Founded in 1868 as
  • Berichte der Deutschen Chemischen Gesellschaft (ISSN 0365-9631, CODEN BDCGAS),

..... Click the link for more information.
digital object identifier (or DOI) is a permanent identifier given to a document, which is not related to its current location. A typical use of a DOI is to give a scientific paper or article a unique identifying number that can be used by anyone to locate details of the paper, and
..... Click the link for more information.
Chemische Berichte (usually abbreviated as Ber. or Chem. Ber.) is a German-language scientific journal featuring chemistry of all disciplines. Founded in 1868 as
  • Berichte der Deutschen Chemischen Gesellschaft (ISSN 0365-9631, CODEN BDCGAS),

..... Click the link for more information.
This article or section contains information about computer software currently in development.
The content may change as the software development progresses.
Google Book Search

Google Book Search screenshot
Developer: Google
OS: Any (web based application)
..... Click the link for more information.
Springer is the name of several places in the United States:
  • Springer, New Mexico
  • Springer Township, North Dakota
  • Springer, Oklahoma
  • Springer Mountain, southern terminus of the Appalachian Trail
Springer is also the name of:

..... Click the link for more information.
Springer is the name of several places in the United States:
  • Springer, New Mexico
  • Springer Township, North Dakota
  • Springer, Oklahoma
  • Springer Mountain, southern terminus of the Appalachian Trail
Springer is also the name of:

..... Click the link for more information.


This article is copied from an article on Wikipedia.org - the free encyclopedia created and edited by online user community. The text was not checked or edited by anyone on our staff. Although the vast majority of the wikipedia encyclopedia articles provide accurate and timely information please do not assume the accuracy of any particular article. This article is distributed under the terms of GNU Free Documentation License.