Long acting beta-adrenoceptor agonist

Information about Long acting beta-adrenoceptor agonist

Long acting beta-adrenoceptor agonists are usually prescribed for moderate to severe persistent asthma patients or patients with COPD. They are designed to replace the shorter acting B2-agonists such as salbutamol, as they have a duration of action of approximately 12 hours in comparison with the 4-6 hour duration of salbutamol, making them ideal candidates for twice-daily administration.

Some long acting beta-adrenoceptor agonists are:

• • [ e] Drugs for obstructive airway diseases: asthma/COPD (R03)
Adrenergics, inhalants	Short acting β₂-agonists: Salbutamol • Fenoterol • Terbutaline Long acting β₂-agonists (LABA): Bambuterol • Clenbuterol • Formoterol • Salmeterol other: Epinephrine • Isoproterenol • Orciprenaline
Glucocorticoids	Beclometasone • Budesonide • Ciclesonide • Fluticasone • Mometasone
Anticholinergics	Ipratropium • Tiotropium
Mast cell stabilizers	Cromoglicate • Nedocromil
Xanthines	Aminophylline • Theobromine • Theophylline
Leukotriene antagonists	Montelukast • Pranlukast • Zafirlukast
Combination products	Budesonide/formoterol • Fluticasone/salmeterol • Ipratropium/salbutamol

Asthma
Classification & external resources

ICD-10 J 45.
ICD-9 493

OMIM 600807
DiseasesDB 1006
MedlinePlus 000141
eMedicine med/177 emerg/43

MeSH C08.127.
..... Click the link for more information.

Salbutamol (INN) or albuterol (USAN) is a short-acting β₂-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and Chronic obstructive pulmonary disease.
..... Click the link for more information.

Salmeterol is a long-acting beta2-adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD. It is currently available as a metered-dose inhaler (MDI) or a proprietary device inhaler.
..... Click the link for more information.

Formoterol (INN) or eformoterol (former BAN) is a long-acting β₂-agonist used in the management of asthma and/or chronic obstructive pulmonary disease (COPD).
..... Click the link for more information.

Bambuterol (INN, marketed by AstraZeneca under the trade names Bambec and Oxeol) is a long acting beta-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline.
..... Click the link for more information.

A section of the Anatomical Therapeutic Chemical Classification System.

R Respiratory system

R03A Adrenergics, inhalants

R03AA Alpha- and beta-adrenoreceptor agonists

R03AA01 Epinephrine

R03AB Non-selective beta-adrenoreceptor agonists

..... Click the link for more information.

Beta₂-adrenergic receptor agonists are a class of drugs used to treat asthma and other pulmonary disease states.
..... Click the link for more information.

Fenoterol is an asthma medication designed to open up the airways to the lungs. It is classed as a beta agonist.

It was a long-acting beta-agonist widely used in New Zealand in the early 1990s but withdrawn because of its association with an excess number of deaths.
..... Click the link for more information.

Terbutaline (trade names Brethine, Bricanyl, or Brethaire) is a β₂-adrenergic receptor agonist, used as a fast-acting bronchodilator (often used as a short-term asthma treatment) and as a tocolytic to delay premature labour.
..... Click the link for more information.

Clenbuterol is a drug prescribed to sufferers of breathing disorders as a decongestant and bronchodilator. People with chronic breathing disorders like asthma use this as a bronchodilator to make breathing easier.
..... Click the link for more information.

Epinephrine (INN) (IPA: [ˌɛpɪˈnɛfrən]) or adrenaline (European Pharmacopoeia and BAN) (IPA: [əˈdrɛnələn]
..... Click the link for more information.

Isoproterenol hydrochloride or isoprenaline (Medihaler-IsoÂ®) is a sympathomimetic beta adrenergic receptor agonist medication.

It is structurally similar to epinephrine but acts for the most part on beta receptors.
..... Click the link for more information.

Orciprenaline (INN, also known as metaproterenol) is a bronchodilator used in the treatment of asthma. Orciprenaline is a moderately selective beta₂-adrenergic receptor agonist that stimulates receptors of the smooth muscle in the lungs, uterus, and vasculature
..... Click the link for more information.

Glucocorticoids are a class of steroid hormones characterised by an ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids are distinguished from mineralocorticoids and sex steroids by the specific receptors, target cells, and effects.
..... Click the link for more information.

Beclometasone dipropionate (INN modified) or beclomethasone dipropionate (USAN, former BAN), also referred to as beclometasone (INN), is a potent Class A glucocorticoid steroid drug. In the form of an inhaler (e.g.
..... Click the link for more information.

Budesonide is a glucocorticoid steroid for the treatment of asthma, non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis. Additionally, it is used for inflammatory bowel disease.
..... Click the link for more information.

Ciclesonide is a glucocorticoid used to treat obstructive airway diseases. It is marketed under the brand name Alvesco for asthma outside the US and Omnaris/Omniair for hayfever in the US.
..... Click the link for more information.

Fluticasone propionate is a potent synthetic corticosteroid often prescribed as treatment for asthma and allergic rhinitis. It is marketed with the brand names Flixotide and Flixonase by Allen & Hanburys, and Flovent, Flonase, and Veramyst
..... Click the link for more information.

Mometasone furoate (also referred to as Mometasone) is a moderately potent glucocorticoid steroid used in the treatment of inflammatory skin disorders (such as eczema and psoriasis), allergic rhinitis (such as hay fever), and asthma for patients unresponsive to less potent
..... Click the link for more information.

An anticholinergic agent is a member of a class of pharmaceutical compounds (such as Dicyclomine) which serve to reduce the effects mediated by acetylcholine in the central nervous system and peripheral nervous system.
..... Click the link for more information.

Ipratropium (as ipratropium bromide, trade name Atrovent) is an anticholinergic drug administered by inhalation for the treatment of obstructive lung diseases. It acts by blocking muscarinic receptors in the lung, inhibiting bronchoconstriction and mucus secretion.
..... Click the link for more information.

Tiotropium (IPA: [ˌtaɪəˈtropiəm]) is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD).
..... Click the link for more information.

Mast cell stabilizers are cromone medications used to prevent or control certain allergic disorders. They block a calcium channel essential for mast cell degranulation, stabilizing the cell and so prevent the release of histamine^[1] and related mediators.
..... Click the link for more information.

Cromoglicate (INN) (also referred to as cromolyn (USAN) or cromoglycate (former BAN)) is traditionally described as a mast cell stabilizer, and is commonly marketed as the sodium salt sodium cromoglicate.
..... Click the link for more information.

Nedocromil sodium is a medication used to prevent wheezing, shortness of breath, and other breathing problems caused by asthma. It is administered by an inhaler under the brand name TiladeÂ®.

Nedocromil is classified as a cromone.
..... Click the link for more information.

This article is copied from an article on Wikipedia.org - the free encyclopedia created and edited by online user community. The text was not checked or edited by anyone on our staff. Although the vast majority of the wikipedia encyclopedia articles provide accurate and timely information please do not assume the accuracy of any particular article. This article is distributed under the terms of GNU Free Documentation License.

EnglishInfo