Nucleus raphe obscurus

Information about Nucleus raphe obscurus

Brain:
Section of the medulla oblongata at about the middle of the olive. (Raphe nuclei not labeled, but 'raphe' labeled at left.)
Latinnucleus raphes obscurus
NeuroNameshier-737
Dorlands/Elsevier n_11/12582817
The nucleus raphe obscurus, despite the implications of its name, has some very specific functions and connections of afferent and efferent nature. The raphe obscurus projects to the cerebellar lobes VI and VII and to crus II along with the nucleus raphe pontis [1].

This so called obscure nucleus has also been implicated in the modulation of the hypoglossal nerve. It has been observed that the ablation of this nucleus causes a change in the firing pattern in the XII nerve [2].

In addition, the raphe obscurus mediates expiration via the inhibitory effect of serotonin and depresses periodic synaptic potentials [3]. It has also been shown that this nucleus stimulates gastrointestinal motor function; microinjections of 5-HT into the n.r. obscurus increase gastric movement [4].

See also

References

1. ^ Brodal, A. Neurological Anatomy in relation to Clinical Medication 3rd ed. Oxford Press. 1981
2. ^ Peever JH, Necakov A, Duffin J., "Nucleus raphe obscurus modulates hypoglossal output of neonatal rat in vitro transverse brain stem slices." Journal of Appl Physiol. 2001 Jan;90(1):269-79
3. ^ Lalley PM, Benacka R, Bischoff AM, Richter DW, "Nucleus raphe obscurus evokes 5-HT-1A receptor-mediated modulation of respiratory neurons". Brain Research Volume 747, Issue 1 , 30 January 1997, Pages 156-159
4. ^ Krowicki, ZK and Hornby, PJ. "Serotonin microinjected into the nucleus raphe obscurus increases intragastric pressure in the rat via a vagally mediated pathway", Pharmacology and Experimental Therapeutics. Volume 265, Issue 1, pp. 468-476, 04/01/1993


 •  • [ e]
Brain: rhombencephalon (hindbrain)
Myelencephalon/medulla
anterior/ventral: Arcuate nucleus of medulla • Pyramid (Decussation) • Olivary body • Inferior olivary nucleus • Anterior median fissure • Ventral respiratory group posterior/dorsal: VII,IX,X: Solitary/tract • XII, X: Dorsal • IX,X,XI: Ambiguus • IX: Inferior salivatory nucleus • Gracile nucleus/Cuneate nucleus/Accessory cuneate nucleus • Area postrema • Posterior median sulcus • Dorsal respiratory group raphe/reticular: Sensory decussation • Reticular formation (Gigantocellular nucleus, Parvocellular reticular nucleus, Ventral reticular nucleus, Lateral reticular nucleus, Paramedian reticular nucleus) • Raphe nuclei (Obscurus, Magnus, Pallidus) tracts: Corticospinal tract (Lateral, Anterior) • Inferior cerebellar peduncle • Olivocerebellar tract • Spinocerebellar (Dorsal, Ventral) • Spinothalamic tract • PCML (Posterior external arcuate fibers, Internal arcuate fibers, Medial lemniscus) • Extrapyramidal (Rubrospinal tract, Vestibulospinal tract, Tectospinal tract)
Metencephalon/pons
Metencephalon/cerebellumVermis • Flocculus • Arbor vitae • Cerebellar tonsil • Inferior medullary velum
Molecular layer (Stellate cell, Basket cell, Parallel fiber) • Purkinje cell layer (Purkinje cell) • Granule cell layer (Golgi cell) • Mossy fibers • Climbing fiber
Deep cerebellar nuclei (Dentate, Emboliform, Globose, Fastigial)
Fourth ventricleapertures (Median, Lateral) • Rhomboid fossa (Vagal trigone, Hypoglossal trigone, Obex, Sulcus limitans, Facial colliculus, Medial eminence) • Lateral recess
Latin}}} 
Official status
Official language of: Vatican City
Used for official purposes, but not spoken in everyday speech
Regulated by: Opus Fundatum Latinitas
Roman Catholic Church
Language codes
ISO 639-1: la
ISO 639-2: lat
..... Click the link for more information.
NeuroNames is a system of nomenclature for the human and/or macaque brain.

It is maintained by the University of Washington and is a part of a tool called "BrainInfo". BrainInfo helps one identify structures in the brain.
..... Click the link for more information.
Elsevier, the world's largest publisher of medical and scientific literature, forms part of the Reed Elsevier group. Based in Amsterdam, the company has substantial operations in the UK, USA and elsewhere.
..... Click the link for more information.
The cerebellum (Latin: "little brain") is a region of the brain that plays an important role in the integration of sensory perception and motor output. Many neural pathways link the cerebellum with the motor cortex—which sends information to the muscles causing them
..... Click the link for more information.
The Pontine raphe nucleus is one of the raphe nuclei. It is located in the pontine tegmentum.


..... Click the link for more information.
The hypoglossal nerve is the twelfth cranial nerve (XII). The nerve arises from the hypoglossal nucleus and emerges from the medulla oblongata in the preolivary sulcus separating the olive and the pyramid. It then passes through the hypoglossal canal.
..... Click the link for more information.
Ablation is defined as the removal of material from the surface of an object by vaporization, chipping, or other erosive processes. The term occurs in space physics associated with atmospheric reentry, in glaciology, medicine and passive fire protection.
..... Click the link for more information.
IMDb profile

For expiration as part of respiration, see .


Expiration (2003) is an independent feature film directed by Gavin Heffernan.
..... Click the link for more information.
Serotonin (pronounced IPA: /ˌsɛrəˈtoʊnən/) (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesized in serotonergic neurons in the central nervous system (CNS) and
..... Click the link for more information.
The raphe nuclei (Latin for 'the bit in a fold or seam') is a moderate-size cluster of nuclei found in the brain stem, and releases serotonin to the rest of the brain.[1]
..... Click the link for more information.
In animals, the brain or encephalon (Greek for "in the skull"), is the control center of the central nervous system, responsible for behavior. The brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing,
..... Click the link for more information.
The rhombencephalon (or hindbrain) is a developmental categorization of portions of the central nervous system in vertebrates.

The rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres.
..... Click the link for more information.
The myelencephalon is a developmental categorization of a portion of the central nervous system. The myelencephalon is composed of the medulla oblongata; contains a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve
..... Click the link for more information.
The medulla oblongata is the lower portion of the brainstem.

Location

By anatomical terms of location, it is rostral to the spinal cord and caudal to the pons, which is in turn ventral to the cerebellum.
..... Click the link for more information.
arcuate nucleus is a group of neurons located on the anterior surface of the medullary pyramids. They receive fibers from the corticospinal tract and send their axons through the external arcuate fibers and striae medullares to the cerebellum via the inferior cerebellar peduncle.
..... Click the link for more information.
The interior district of the medulla oblongata is named the pyramid and lies between the anterior median fissure and the antero-lateral sulcus.

Its upper end is slightly constricted, and between it and the pons the fibers of the abducent nerve emerge; a little below the
..... Click the link for more information.
pyramidal decussation.

Having crossed the middle line, they pass down in the posterior part of the lateral funiculus as the lateral cerebrospinal fasciculus.

Additional images



Diagrams of the medulla spinalis.

..... Click the link for more information.
In anatomy, the olivary bodies or simply olives (Latin oliva and olivae, singular and plural, respectively) are a pair of prominent oval structures in the medulla oblongata, the lower portion of the brainstem. They contain the olivary nuclei.
..... Click the link for more information.
The inferior olivary nucleus is the largest nucleus situated in the olivary body, part of the medulla oblongata.

It consists of a gray folded lamina arranged in the form of an incomplete capsule, opening medially by an aperture called the hilum.
..... Click the link for more information.
The anterior median fissure (ventral or ventromedian fissure) contains a fold of pia mater, and extends along the entire length of the medulla oblongata: it ends at the lower border of the pons in a small triangular expansion, termed the foramen cecum.
..... Click the link for more information.
The ventral respiratory group (VRG) is a column of neurons located in the ventrolateral region of the medulla, extending from the caudal facial nucleus to -400μm obex.
..... Click the link for more information.
The solitary nucleus and tract are structures in the brainstem that carry and receive visceral sensation and taste from the facial (VII), glossopharyngeal (IX), vagus (X) cranial nerves, as well as the cranial part of the accessory nerve (XI).
..... Click the link for more information.
The solitary tract (Latin: tractus solitarius) is a compact fiber bundle that extends longitudinally through the posterolateral region of the medulla. The solitary tract is surrounded by the nucleus of the solitary tract, and descends to the upper cervical segments
..... Click the link for more information.
The hypoglossal nucleus is a cranial nerve nucleus, and it extends the length of the medulla, and being a motor nucleus, is close to the midline. In the open medulla, it is visible as what is known as the hypoglossal trigone
..... Click the link for more information.
The dorsal nucleus of the vagus nerve (or posterior motor nucleus of vagus) is a cranial nerve nucleus for the vagus nerve that arises from the floor of the fourth ventricle.
..... Click the link for more information.
The nucleus ambiguus (literally "ambiguous nucleus") is a region of histologically disparate cells located just dorsal (posterior) to the inferior olivary nucleus in the lateral portion of the upper (rostral) medulla.
..... Click the link for more information.
In the brain, the inferior salivatory nucleus is a cluster of neurons controlling the parasympathetic input to the parotid gland. It is one of the components of the glossopharyngeal nerve (cranial nerve IX).
..... Click the link for more information.
Located in the medulla oblongata, the gracile nucleus is one of the dorsal column nuclei that participates in the sensation of fine touch and proprioception. It contains second-order neurons of the dorsal column-medial lemniscus system which receive inputs from sensory neurons of
..... Click the link for more information.
One of the dorsal column nuclei, the cuneate nucleus is a wedge-shaped nucleus in the closed part of the medulla oblongata. It contains cells that give rise to the cuneate tubercle, visible on the posterior aspect of the medulla.
..... Click the link for more information.
The accessory cuneate nucleus is located lateral to the cuneate nucleus in the medulla oblongata at the level of the sensory decussation (the crossing fibers of the posterior column/medial lemniscus tract).
..... Click the link for more information.

This article is copied from an article on Wikipedia.org - the free encyclopedia created and edited by online user community. The text was not checked or edited by anyone on our staff. Although the vast majority of the wikipedia encyclopedia articles provide accurate and timely information please do not assume the accuracy of any particular article. This article is distributed under the terms of GNU Free Documentation License.