Vaginal rings (also known as intravaginal rings, or V-Rings) are polymeric drug delivery devices designed to provide controlled release of drugs for intravaginal administration over extended periods of time. The ring is inserted into the vagina and provides contraception protection. Vaginal rings come in one size that fits most women.
Types of Vaginal Rings
Several vaginal ring products are currently available, including:
- Vaginal rings as treatment of peri-menopausal symptoms:
- Estring - a low-dose estradiol-releasing ring, manufactured from silicone elastomer, for the treatment of vaginal atrophy (atrophic vaginitis).
- Femring - a low-dose estradiol-acetate releasing ring, manufactured from silicone elastomer, for the relief of hot flashes and vaginal atrophy associated with menopause.
- Vaginal rings as contraception:
- NuvaRing - a low-dose contraceptive vaginal ring, manufactured from poly(ethylene-co-vinyl acetate), and releasing etonogestrel (a progestin) and ethinylestradiol (an estrogen).
- Progering - containing progesterone as a sole ingredient, is available only in Chile and Peru.
- Annovera - a contraceptive vaginal ring, manufactured from methyl siloxane-based polymers, and releasing segesterone acetate (a progestin) and ethinylestradiol (an estrogen)
A number of other vaginal ring products are also in development.
The combined hormonal contraceptive vaginal ring is self-administered once a month. Leaving the ring in for three weeks slowly releases hormones into the body, mainly vaginally administered estrogens and/or progestogens (a group of hormones including progesterone) - the same hormones used in birth control pills. These hormones work mostly by stopping ovulation and thicke... ...read more